Midline Glossectomy

Table of Contents

Midline Glossectomy Introduction

Midline glossectomy is a surgical procedure used to treat obstructive sleep apnoea (OSA) and snoring, particularly when the tongue base is a major contributor to airway obstruction during sleep. The procedure removes a central strip of tissue from the back of the tongue via the mouth to create more space and reduce airway collapse.

It is often performed as part of multilevel surgery alongside other procedures such as uvulopalatopharyngoplasty (UPPP), Transpalatal Advancement (TPA), or nasal surgery, depending on the level(s) of airway narrowing.

Reasons for surgery

Midline glossectomy may be recommended if you have:

  • Obstructive Sleep Apnoea (OSA) that is moderate to severe
  • Snoring that disrupts bed partners or household members
  • Intolerance or failure of CPAP therapy the standard non-surgical treatment
  • Evidence of tongue base collapse on sleep endoscopy
  • Residual OSA after previous surgery (e.g., palate or nasal procedures)
  • Upper airway resistance syndrome with documented tongue-related obstruction

This procedure is typically offered when non-surgical measures have not been successful or are poorly tolerated.

Benefits of the procedure

  • Reduced or eliminated snoring & reduced partner complaints/distress
  • Improved breathing during sleep
  • Cure or significant reduction in OSA severity
  • Better sleep quality and reduced daytime sleepiness
  • Improved oxygen levels during the night
  • Reduced long-term health risks related to untreated OSA (e.g. high blood pressure, heart disease, stroke)
  • Improved quality of life

Risks & complications

As with any surgical procedure, there are associated risks:

  • Pain in the throat or tongue for 1–2 weeks
  • Swelling of the tongue (can rarely affect breathing)
  • Bleeding, which may require intervention
  • Temporary changes in taste
  • Infection
  • Swallowing difficulties or globus sensation (usually short-lived)
  • Temporary speech or articulation changes
  • Rare: Temporary hypoglossal nerve irritation (<1%) or permanent nerve injury (extremely rare)
  • Persistent or recurrent snoring/OSA, particularly if severe OSA or obesity present

These risks will be discussed with you by Dr Phillips based on your specific anatomy and clinical context.

Alternative treatments

Non-surgical treatment options include:

  • CPAP therapy – very effective but not always tolerated
  • Mandibular advancement splints (oral devices) – suitable for mild to moderate OSA
  • Lifestyle changes such as weight reduction, alcohol moderation, and sleep posture adjustment
  • Nasal surgery – may be needed to address nasal obstruction or optimise CPAP/oral appliance use

These options may be trialled first or used in combination with surgery.

Pre-operative instructions

Fasting

  • No food for 6 hours before surgery
  • Clear fluids (e.g., water, black tea/coffee) allowed until 2 hours prior

Medications

  • Advise Dr Phillips of any medications you take
  • You may need to temporarily stop blood thinners

Illness

  • Notify the clinic if you are unwell before your procedure — surgery may need to be rescheduled for safety

Procedure details

  • Performed under general anaesthetic
  • Takes approximately 60–90 minutes
  • All work is done inside the mouth
  • A vertical strip of tongue base tissue is removed to reduce volume and collapse
  • Dissolvable stitches are used
  • Patients stay overnight for observation

Post-operative care & recovery

Pain

  • Expected for 7–14 days
  • Use regular paracetamol and ibuprofen
  • Stronger medications (e.g., tapentadol, oxycodone) may be prescribed for short-term use

Diet

  • Start with soft, cool foods (e.g., yoghurt, mashed vegetables, smoothies)
  • Avoid spicy, acidic, or rough foods
  • Maintain hydration

Activity

  • Rest for 1–2 weeks
  • Avoid exercise, lifting, and strenuous activity
  • Most patients return to work after 10–14 days

Bleeding

  • Minor blood-stained saliva is common
  • Bright red bleeding or large clots require urgent review

What to watch for

Seek urgent care if you experience:

  • Bright red bleeding
  • Difficulty breathing or tongue swelling
  • Inability to swallow fluids
  • Fever above 38.5°C
  • Signs of dehydration

Follow-up instructions

You will be reviewed by Dr Phillips 1–2 weeks post-operatively. If further sleep testing is required, this will be arranged to assess the outcome of your surgery.

References

Murphey AW, Kandl JA, Nguyen SA, Weber AC, Gillespie MB. The Effect of Glossectomy for Obstructive Sleep Apnea: A Systematic Review and Meta-analysis. In: Otolaryngology – Head and Neck Surgery (United States). SAGE Publications Inc.; 2015. p. 334–42.

Frequently asked questions (FAQ)

  • Will this cure my OSA or snoring?

    Surgery can significantly reduce symptoms and improve sleep, especially in patients with tongue-related obstruction. Complete resolution may not occur in all patients, particularly if other levels of obstruction exist.

  • What evidence supports this procedure?

    A 2015 systematic review and meta-analysis of 18 studies (522 patients) evaluating glossectomy techniques, including midline glossectomy, showed:

    • AHI reduced by 27.8 events/hr (average)
    • Epworth Sleepiness Scale improved by 5.5 points
    • Snoring improved by 5.6 points on a visual analogue scale
    • Lowest oxygen saturation (LSAT) improved by 7.7%
    • Complication rate: 16.4%, with taste change (5.8%) and bleeding (4.2%) being the most common, usually temporary

    These findings support the use of midline glossectomy as an effective part of multilevel airway surgery.

  • Will I still need CPAP?

    Possibly — but surgery often makes CPAP easier to tolerate or reduces the pressure required. In some cases, it may no longer be necessary.

  • Is it painful?

    Yes, but manageable. Pain peaks around days 5–7 and improves with regular medication and hydration. Pain relief and hydration are key to recovery.

  • Will my swallowing or speech be affected?

    Mild, temporary changes are common. Permanent changes are rare, especially with modern techniques that preserve tongue function and sensation.

Book a consultation

If you’d like to discuss this procedure or explore suitable treatment options, please get in touch with Dr Nicholas Phillips’ clinic.